Health is among the key areas of prime concern among most people. With the advent of the discipline of medicine, health has been improved a great deal. Extensive research has been conducted in the past, and is still an ongoing process, in a bid to curb and eliminate all sorts of health problems. Among the recent breakthroughs is concerned with liposomal formulation.
The process of this formulation was discovered 50 years ago. It came about as a solution to a problem of drugs taken orally being exhausted and digested before reaching the intended target areas. The liposomal way was deemed best suited since it was a favorable carrier to both hydrophilic and hydrophobic drugs.
The structural composition of the liposomes was adequately suited for the job at hand. It is composed of a mainly liquid core. This is enveloped by a layer of phospholipids, which could be either synthetic or natural. The drugs to be transported, depending on their chemical composition, would either attach to the core or upper layers without being destroyed or denatured.
The main advantage of using liposomes comes from its core structure. The procedure of formation is key to this. They are formed when a specific heat level is exposed to phospholipids immersed in water. This provides the right atmosphere for formation of liposomes. The physiochemical composition should then be deduced so as to enable the liposome act as an appropriate carrier for an appropriate drug - given its composition to avoid any reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
Further research and development on cancer and other terminal ailments have had positive results, and the outcomes lauded by the medical community as well as the general public. Research and testing of liposomes as anti- cancer drug carriers has brought about drugs which are n testing. These include doxorubicin, , lipoplatin, paclitaxel, aroplatin and cisplatin.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The use of liposomes as a carrier for dietary supplements is a newer idea that I undergoing further research. The idea is to use the same technique as the currently successful targeted drug delivery to deliver various supplements taken orally to specific areas in the body. This is however still undergoing research and testing. The use of liposomes in creation of various drugs and vaccines has led to a huge leap in terms of drug research and development. The process of the formulation has thus been lauded as wielding enormous potential for development of better medical solutions for a lot of persistent medical conditions.
The process of this formulation was discovered 50 years ago. It came about as a solution to a problem of drugs taken orally being exhausted and digested before reaching the intended target areas. The liposomal way was deemed best suited since it was a favorable carrier to both hydrophilic and hydrophobic drugs.
The structural composition of the liposomes was adequately suited for the job at hand. It is composed of a mainly liquid core. This is enveloped by a layer of phospholipids, which could be either synthetic or natural. The drugs to be transported, depending on their chemical composition, would either attach to the core or upper layers without being destroyed or denatured.
The main advantage of using liposomes comes from its core structure. The procedure of formation is key to this. They are formed when a specific heat level is exposed to phospholipids immersed in water. This provides the right atmosphere for formation of liposomes. The physiochemical composition should then be deduced so as to enable the liposome act as an appropriate carrier for an appropriate drug - given its composition to avoid any reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
Further research and development on cancer and other terminal ailments have had positive results, and the outcomes lauded by the medical community as well as the general public. Research and testing of liposomes as anti- cancer drug carriers has brought about drugs which are n testing. These include doxorubicin, , lipoplatin, paclitaxel, aroplatin and cisplatin.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The use of liposomes as a carrier for dietary supplements is a newer idea that I undergoing further research. The idea is to use the same technique as the currently successful targeted drug delivery to deliver various supplements taken orally to specific areas in the body. This is however still undergoing research and testing. The use of liposomes in creation of various drugs and vaccines has led to a huge leap in terms of drug research and development. The process of the formulation has thus been lauded as wielding enormous potential for development of better medical solutions for a lot of persistent medical conditions.
About the Author:
You can visit purensm.com for more helpful information about Medical Breakthroughs From Liposomal Formulation.
No comments:
Post a Comment