Tuesday, February 3, 2015

What The Liposomal Encapsulation Means To Clinical Therapy

By Kristen Baird


The utilization of liposome in medical sector started in the mid-1960s, and is currently regarded as one of the medical innovation in the 20th century. Though still young in clinical medicine, liposomal encapsulation technology simply referred to as LET has gained popularity as a possible replacement of most medical administration methods currently in place.

There is a general concurrence in the field of medicine and in the area of science as a whole that LET is the technology that is most likely to replace the capsule, needles, serum, and tablets as the most preferred method of drug administration. The clinical trials have demonstrated with no doubt that LET offers a unique solution in the treatment of racehorse with no need of needles.

In this technology, phospholipid membrane (liposome) is used to encase a prescribed amount of pharmaceutical compounds with the aim of preventing their degradation as they pass through the gastrointestinal tract. This option offers an excellent transfer mechanism that is not available with other drug administration methods. The method is now used in other fields other than in clinical therapies. These include supplement manufacturers, topical moisturizers and the beauty product manufacturers among others.

Phospholipid liposome can withstand the effect of anyone radicals, especially the chemicals, the body dampness, the basic liquids, and the salts inside the digestive tract. The substance enclosed is therefore secured till it gets to the targeted tissue where the cell walls of the tissue cells open allowing the phospholipids and its content inside. The result is a superb method of drug therapy that has minimum impact to functionality of normal body system.

The effectiveness of this technology relies on the fact that liposomes easily penetrate cell walls and many other infectious biofilms, which allows for a highly effective delivery system against these pathological infections. Research has found that 5 grams of Vitamin C encased in liposomes is as effective as 50 grams of Vitamin C that is delivered intravenously demonstrating how effective this technology is in terms of delivery of compounds to the targeted tissues.

Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.

The introduction of phospholipids into the body comes with its own merits. It eliminates serum lipids, diminishes platelet collection, cholesterol, triglyceride, and expands promotes good cholesterol. Notwithstanding this, it helps support immunity, enhances nature of memory, secures the liver and enhances one's capacity to persist exercise.

Even though the LET promises to be the most effective method of drug delivery, the old age methods such as capsules, tablets, powder forms and needles must still remain in use. These methods do not disrupt the blood flow in the system which is essential for physical fitness. Ideally, a comprehensive method that considers all the available methods would be better for any clinical therapy.




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